Mary Hudson Scott was a Quaker who resided in Perquimans Precinct by 1680. Though her maiden name is unknown, she married Henry Hudson, who died in 1680. Later in 1683 she married Joseph Scott, who died in 1685. Mary and Joseph hosted a Quaker congregation, using their own home as a meeting house. After Joseph's death, Mary Scott took over the indenture of Sanders, an American Indian man, for the term of eighty years. When Mary died in Perquimans Precinct in about September 1692, she passed the ownership of the indenture over to her daughter Juliana.