Simon Foscue was born in Virginia in about 1675. He arrived in North Carolina by 1704, settling in Hyde County, where he received a land grant in about 1704. According to a petition Foscue submitted to the North Carolina Council in 1746, sometime after settling in Hyde, possibly during the Tuscarora War, Foscue "was shot in the Head his wife and children taken Prisoners and carryed away, [and] his House burnt down to the Ground." Foscue eventually recovered and remarried and he died in Hyde County in about 1751.